Adverse Events Profile of PrePex a Non-Surgical Device for Adult Male Circumcision in a Ugandan Urban Setting
Published at PLOS ONE January 28, 2014. DOI: 10.1371/journal.pone.0086631
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A prospective study, conducted in Uganda between August and October 2012 was assessed to profile Adverse Event rate and acceptance of PrePex.
625 subjects underwent the PrePex circumcision. 12 moderate Adverse Events occurred among 10 participants (1.9%): 5 had device displacement, 1 had an averted foreskin; 5 had bleeding after the device was removed and 1 had voiding difficulties. Adverse Events of a moderate or severe nature associated with PrePex were low and reversible. PrePex was found to be feasible for male circumcision scale up.
PrePex was evaluated for adverse events (AE) rate among men in Uganda and found to be a viable option for scaling up of safe male circumcision with a low rate of AE. Use of Prepex would not exclude the conventional surgical circumcision since some may be screened out or may require surgical circumcision to address AEs.