HIV Prevention: Male Circumcision Comparison Between a Nonsurgical Device to a Surgical Technique in Resource-Limited Settings: A Prospective, Randomized, Nonmasked Trial
Published manuscript at the Journal of Acquired Immune Deficiency Syndromes (JAIDS): 1 September 2012 ,Volume 61, Issue 1, p 49–55. Click here for the full article
This study was the second clinical evaluation of PrePex device based on World Health Organization suggested framework for evaluating Male circumcision devices, and was designed to compare PrePex with surgical MC, verifying the viability of the MC scale-up goal.
PrePex male circumcision was found to be superior to surgical MC as measured by procedure time. Rwanda selected PrePex for national scale up.
The randomized controlled study was conducted in Rwanda during 2011 comparing the non-surgical PrePex with no injected anesthesia to surgical male circumcision under local anesthesia on 144 PrePex subjects vs. 73 surgical subjects. The study results demonstrated superiority of PrePex over surgery in various areas, including procedure time